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KMID : 1134820130420081263
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Journal of the Korean Society of Food Science and Nutrition
2013 Volume.42 No. 8 p.1263 ~ p.1269
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Inhibitory Effects of Histamine Production in Mackerel Muscle by Medicinal Herbs and Seaweed Extracts
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Jung Seul-A
Kim Dong-Hyun
Kim Koth-Bong-Woo-Ri
Kim Hyun-Jee
Jeong Da-Hyun
Kang Bo-Kyeong
Bark Si-Woo
Pak Won-Min
Kim Bo-Ram
Byun Myung-Woo
Ahn Dong-Hyun
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Abstract
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This study was conducted in order to investigate the inhibitory effects of natural materials on histamine production in mackerel. Antimicrobial activities on Photobacterium phosphoreum of medicinal herbs and seaweeds were investigated using the paper disc assay and MIC (minimum inhibitory concentration) test. According to the results, Sargassum sagamianum and Ecklonia cava ethanol extracts exhibited antibacterial activity. In particular, Sargassum sagamianum ethanol extract showed excellent antibacterial activity at 0.015625 mg/mL by the MIC test. Anti-histamine release activities of natural materials were further investigated by examining their inhibitory effects on histidine decarboxylase (HDC) activity in the crude enzyme preparation from Photobacterium phosphoreum. The ethanol extracts of Ecklonia cava and Eisenia bicyclis exhibited the strongest HDC inhibitory activity, with 32% and 22%, at a concentration of 1 mg/mL, respectively. Therefore, natural materials may reduce histamine poisoning through decrease of histamine production in mackerel.
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KEYWORD
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medicinal herb, seaweed, mackerel muscle, histidine decarboxylase
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